The Big Bang Theory Season 5 Episode 16 : The Vacation Solution
Sheldon is forced to take a vacation by the university president. After trying to sneak into work, Sheldon goes to help Amy in her biology lab. She has him cleaning laboratory glassware and counting growth cultures in Petri dishes and failing at both tasks. Sheldon insists that with his intelligence he can do more. When Amy lets him try to dissect a brain, he faints after he cuts his thumb. He ends up at a bar, drinking virgin piña coladas at the Cheesecake Factory bar with Howard.